Advances in sequencing techniques have massively increased the publicly accessible -omics data and thus enable further and more extensive research opportunities on genome diversity. The concept of the pangenome refers to the union of gene families shared by a set of genomes. Several studies have implemented specific pangenome analyses for a variety of organisms, ranging from microbes to viruses and plants , leading to genomic projects of various scales and the advancement of general understanding of evolutionary mechanisms, generating usable knowledge across multiple sectors.

The research on epileptiform discharges (ED) in electroencephalographic recordings of patients with epilepsy has shown that changes are observed in connectivity of the brain area correlation networks. The data processed describe various epileptiform discharge situations. In some cases, the technique of transcranial magnetic stimulation (TMS), a noninvasive stimulation technique applicable in the field of focal epilepsy treatment, is used. In the current study, we examine the connectivity change of networks, formed by analyzing the correlation of selected EEG channels using cross correlation and cross mutual information networks.